THE CHROMATIN AND SINGLE-CELL TRANSCRIPTIONAL LANDSCAPES OF CD4 T CELLS IN INFLAMMATORY BOWEL DISEASE LINK RISK LOCI WITH A PROINFLAMMATORY TH17 CELL POPULATION

The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population

IntroductionThe imbalance between Hayward LED WaterBowl Th17 and regulatory T cells in inflammatory bowel diseases (IBD) promotes intestinal epithelial cell damage.In this scenario, T helper cell lineage commitment is accompanied by dynamic changes to the chromatin that facilitate or repress gene expression.MethodsHere, we characterized the chromat

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Pore structure characterization and its influence on aqueous phase trapping damage in tight gas sandstone reservoirs.

Aqueous phase trapping (APT), which is one of the most prominent damages, seriously restricts the natural gas production in tight gas sandstone with low permeability.Pore size and microscopic pore structures are the most important factors to determine the water blocking damage.In this paper, 9 core samples from tight gas sandstone with various phys

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